English
New research/ Prebiotic dietary fibre may support emotional
2024.10.16
A new study, conductedby Jackson et al.i , demonstrates that the intake of theprebiotic dietary fibre oligofructose alone, or in combination with the humanmilk oligosaccharide 2’fucosyllactose, promotes a significant increase inBifidobacteria in the gut and can result in substantial improvements in mood1 inhealthy adults with mild to moderate feelings of anxiety and depression.
Two out of threeconsumers across the globe already see the importance of their gut on mood,saying that their digestive health has an influence on their mental wellbeingand stress levelsii. Thanks to the gut-brain axis, important moodparameters can be influenced via microbiota modulation. With mental healthdisorders such as anxiety and depression an increasing burden to the healthsystems globallyiii, using a diet-approach that positivelyinfluences microbiota using gut-friendly food is an attractive proposition fordecreasing public health costs and supporting healthy living.
The study, which ranover five weeks (1 week run-in and 4 weeks intervention), aimed to look at theeffect of the chicory root fibre oligofructose and the human milkoligosaccharide 2’fucosyllactose on intestinal colonisation and their abilityto reduce anxiety and depression. The 92 subjects chosen for the study werehealthy and had mild to moderate levels of anxiety and depression. Using arandomised, double blind, placebo-controlled, parallel designed methodology,the subjects were split into four groups of 23 and given either 8g ofoligofructose plus 2g of maltodextrin per day, 8g of oligofructose plus 2g of2’fucosyllactose per day, 2g of 2’fucosyllactose plus 8g of maltodextrin perday, or 10g of maltodextrin per day.
The results showedthat at the end of the four-week intervention period, those participants takingthe prebiotic oligofructose on its own, or in combination with2’fucosyllactose, experienced significant increases in beneficial gut bacteria,including Bifidobacterium,Bacteroides, Roseburia and Faecalibacterium prausnitzii, comparedto the control group. Additionally, those taking oligofructose on its own or incombination with 2’fucosyllactose also significantly outperformed the controlgroup in improvements in several mood state parameters.
Commenting on thefindings, Dr Stephan Theis, Head of Nutrition Science at BENEO said: “Thanks tothis study, an important piece of scientific evidence has been contributed tothe fascinating science of the gut-brain-axis. The results add to the growing bodyof evidence showing that the composition of gut microbiota and resultingmetabolites impact mood state. The findings also demonstrate that targetedinfluence with prebiotics may be a viable way to improve mood. It is notablethat oligofructose has once again been shown to have a significant effect onbeneficial microbiota and is an essential contributor to the beneficial effectson gut microbiota and mood parameters when combined with 2’fucosyllactose.”
Joyfulchem can supply :
- Inulin from Chicory root/ Jerusalem artichoke root
- Oligofructose
- Beta-glucan from Oat/Yeast
Contact
Leave your information and we will contact you.